10 people in space right now:
4 on the just-launched STS-135 space shuttle Atlantis (Final shuttle mission):
Christopher Ferguson, Douglas Hurley, Sandra Magnus, Rex Walheim.
6 already on the ISS:
Soyuz-TMA21: Aleksandr Samokutyayev, Andrei Borisenko, Ronald J. Garan, Jr. (Launched April, landing September).
Soyuz TMA-02M: Sergeyb Volkov, Michael E. Fossum, Satoshi Furukawa. Planned landing November.
Soyuz TMA-22 September 30, 2011.
Also unmanned Juno space probe (to Jupiter) launching August 5, 2011.
NASA's ISS page.